Guinea-Bissau President Umaro Sissoco Embaló has dismissed five government ministers, without giving any explanation for their sacking.
The ministers for defence, interior, economy, agriculture and energy were all dismissed in a decree on Sunday.
Their dismissal comes ahead of a parliamentary debate on Monday on which political alliances have the right to govern the country.
The country has been facing political disorder for many years. Guinea-Bissau has had nine coups or attempted coups since 1980.
Embaló, a former army general, has said he wants to resolve tensions and modernise Guinea-Bissau – one of the world’s poorest nations.
President Embaló was announced as the winner of December’s election, but the long-time ruling party PAIGC said the elections were rigged.